Acetone → N*2*-Isopropyl-N*1*-(8-methoxy-2-methylquinolin-4-yl)-1-phenylethane-1,2-diamine

HRID 1966542Notes

Reaction equation

HRID 1966542 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[N:11]=[C:10]([CH3:13])[CH:9]=[C:8]2[NH:14][CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:16][NH2:17].[CH3:24][C:25]([CH3:27])=O>>[CH:25]([NH:17][CH2:16][CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[NH:14][C:8]1[C:7]2[C:12](=[C:3]([O:2][CH3:1])[CH:4]=[CH:5][CH:6]=2)[N:11]=[C:10]([CH3:13])[CH:9]=1)([CH3:27])[CH3:24]

Participants

3

Reactant 2

HCID 180AcetoneHCID 70276090N*1*-(8-Methoxy-2-methylquinolin-4-yl)-1-phenylethane-1,2-diamine

Product 1

HCID 59474739N*2*-Isopropyl-N*1*-(8-methoxy-2-methylquinolin-4-yl)-1-phenylethane-1,2-diamine

Procedure

Preparation was made using a similar procedure as described in example 79. Starting materials were N*1*-(8-methoxy-2-methylquinolin-4-yl)-1-phenylethane-1,2-diamine (Example 75) and acetone.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-022b9411f85c4fa9951f2bb4780445ee
Source dataset
uspto-grants-2013_04
Patent number
US08420670B2

Reaction notes

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