4-Chloro-8-methoxy-2-methylquinoline → (3-Chloro-4-trifluoromethylbenzyl)-(8-methoxy-2-methylquinolin-4-yl)-amine

HRID 1966543Notes

Reaction equation

HRID 1966543 reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[Cl:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[C:24]([F:27])([F:26])[F:25])[CH2:19][NH2:20]>>[Cl:15][C:16]1[CH:17]=[C:18]([CH:21]=[CH:22][C:23]=1[C:24]([F:25])([F:26])[F:27])[CH2:19][NH:20][C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1

Participants

3

Reactant 2

HCID 8075834-Chloro-8-methoxy-2-methylquinolineHCID 235127443-Chloro-4-(trifluoromethyl)benzylamine

Product 1

HCID 59474795(3-Chloro-4-trifluoromethylbenzyl)-(8-methoxy-2-methylquinolin-4-yl)-amine

Procedure

Preparation was made using a similar procedure as described in example 1, method 1.3. Starting materials were 4-chloro-8-methoxy-2-methylquinoline and 3-chloro-4-trifluoromethylbenzylamine.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-a61f91a9041c43a0bd8ff74eaf1f5acc
Source dataset
uspto-grants-2013_04
Patent number
US08420670B2

Reaction notes

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