4-Chlorobenzylamine → (4-Chlorobenzyl)-(2-methyl-8-methoxyquinolin-4-yl)amine
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:14])[CH:3]=1.[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][NH2:21])=[CH:18][CH:17]=1>>[Cl:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][NH:21][C:2]2[C:11]3[C:6](=[C:7]([O:12][CH3:13])[CH:8]=[CH:9][CH:10]=3)[N:5]=[C:4]([CH3:14])[CH:3]=2)=[CH:18][CH:17]=1Participants
3
Procedure
Preparation was made using a similar procedure as described in example 1, method 1.3. Starting materials were 4-chloro-2-methyl-8-methoxyquinoline and 4-chlorobenzylamine.
Workup
- customPreparation
Sources & evidence
- ORD record
- ord-ab2921d1ce5a49d9a4c91a71f7957be9
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08420670B2
Reaction notes
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