4-Chloro-2-methylquinoline → (2,3-Dichloro-benzyl)-(2-methylquinolin-4-yl)-amine
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:12])[CH:3]=1.[Cl:13][C:14]1[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:15]=1[CH2:16][NH2:17]>>[Cl:13][C:14]1[C:21]([Cl:22])=[CH:20][CH:19]=[CH:18][C:15]=1[CH2:16][NH:17][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([CH3:12])[CH:3]=1Participants
3
Procedure
Preparation was made using a similar procedure as described in example 1, method 1.3. Starting materials were 4-chloro-2-methylquinoline and 2,3-dichlorobenzylamine.
Workup
- customPreparation
Sources & evidence
- ORD record
- ord-61eb83d5d3834fbbbe50589f9ae2a257
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08420670B2
Reaction notes
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