HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 6,6-Dimethyl-3-(6-(phenylethynyl)pyridazin-3-yl)-1,3-oxazinan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 2-Methyl-4-(6-phenylethynyl-pyridazin-3-ylamino)-butan-2-ol | HCID 57516775 | — |
| Product | 6,6-Dimethyl-3-(6-(phenylethynyl)pyridazin-3-yl)-1,3-oxazinan-2-one | HCID 53494699 | — |
Reaction Steps
The title compound, a crystalline light yellow solid, MS: m/e=308.3 (M+H+), was prepared in accordance with the general method of Example 152, step 2 starting from 2-methyl-4-(6-phenylethynyl-pyridazin-3-ylamino)-butan-2-ol (Example 153, step 1) and triphosgene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420661B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-ac2ab97e3d3747a780c3a09f9173e1e5 |
| Source note | uspto-grants-2013_04 |