1-(4-Phenylbutoxy)hept-6-en-3-ol → 1-(4-Phenylbutoxy)hept-6-en-3-one

HRID 1966623Notes

Reaction equation

HRID 1966623 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][CH:14]([OH:19])[CH2:15][CH2:16][CH:17]=[CH2:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(CCCCOCCC=O)C=CC=CC=1>>[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][O:11][CH2:12][CH2:13][C:14](=[O:19])[CH2:15][CH2:16][CH:17]=[CH2:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 672444321-(4-Phenylbutoxy)hept-6-en-3-olHCID 866583073-(4-Phenylbutoxy)propionaldehyde

Product 1

HCID 672462231-(4-Phenylbutoxy)hept-6-en-3-oneYield 93.6%

Procedure

Obtained from Intermediate 14 (0.41 g, 1.56 mmol) by the procedure described for the Intermediate 13. Purification by column chromatography with silica gel and methylene chloride/acetone (20:1) as eluent gave the title compound (0.38 g, 88%) as oil.

Workup

  1. customPurification by column chromatography with silica gel and methylene chloride/acetone (20:1) as eluent

Sources & evidence

ORD record
ord-549fd6792c7e43fa9fcfc14e05905a6f
Source dataset
uspto-grants-2013_04
Patent number
US08420669B2

Reaction notes

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