2,2,3,3-Tetrafluoro-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}butan-1-ol → 2,2,3,3-Tetrafluoro-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}butanal

HRID 1966637Notes

Reaction equation

HRID 1966637 reaction equation
[F:1][C:2]([F:19])([C:5]([F:18])([F:17])[CH2:6][O:7][CH2:8]/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH2:3][OH:4].C1(CCCCOCCC=O)C=CC=CC=1>>[F:1][C:2]([F:19])([C:5]([F:17])([F:18])[CH2:6][O:7][CH2:8]/[CH:9]=[CH:10]/[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[CH:3]=[O:4]

Participants

3

Reactant 2

HCID 866276442,2,3,3-Tetrafluoro-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}butan-1-olHCID 866583073-(4-Phenylbutoxy)propionaldehyde

Product 1

HCID 866583102,2,3,3-Tetrafluoro-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}butanal

Procedure

Obtained from Intermediate 37 (1.80 g, 6.47 mmol) by the procedure described in Intermediate 13. 2,2,3,3-Tetrafluoro-4-{[(2E)-3-phenylprop-2-en-1-yl]oxy}butanal was obtained (1.37 g, 77%) as oil.

Sources & evidence

ORD record
ord-1a1dfcadd78f4a9db4669ae3e42ff631
Source dataset
uspto-grants-2013_04
Patent number
US08420669B2

Reaction notes

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