HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-ol → 1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-ol | HCID 67245398 | — |
| Reactant | 3-(4-Phenylbutoxy)propionaldehyde | HCID 86658307 | — |
| Product | 1-(2,2-Difluoro-2-phenylethoxy)hept-6-en-3-one | HCID 67246812 | 43% |
Reaction Steps
Obtained from Intermediate 83 (4.3 g, 15.8 mmol) by the procedure described in Intermediate 13. Purification by column chromatography with silica gel eluting with ethyl acetate/n-hexane (1:5) gave the title compound (1.82 g, 43%) as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420669B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-f9bae78385484de4bf868462171218cb |
| Source note | uspto-grants-2013_04 |