HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → HCID 178493720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | HCID 58541913 | HCID 58541913 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178493720 | HCID 178493720 | 100% |
Reaction Steps
3-[1-tert-Butyl-5-(5-methoxy-pyridin-3-yl)-1H-benzimidazol-2-yl]-benzonitrile (0.480 g, 1.255 mmol) is dissolved in ethanol (5 mL). Hydroxylamine (1.0 mL, 50% in water) is added. The reaction mixture is heated under reflux for 6 hours. The solvent is removed in vacuum to give 3-[1-tert-butyl-5-(5-methoxy-pyridin-3-yl)-1H-benzimidazol-2-yl]-N-hydroxy-benzamidine (0.531 g, 100%) as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420655B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-a6e1818a71604c91af6c7f5fd4369ba1 |
| Source note | uspto-grants-2013_04 |