HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane → 5,8-Dioxaspiro[3.4]octane-2-methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(Benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane | HCID 12073582 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5,8-Dioxaspiro[3.4]octane-2-methanol | HCID 12073583 | — |
Reaction Steps
Palladium/carbon (10%) was added to a solution of 2-[(benzyloxy)methyl]-5,8-dioxaspiro[3.4]octane (22.0 gm, 94.0 mmol) (step c) in methanol and the mixture was stirred at room temperature under hydrogen balloon for about 4 hours. It was filtered through celite bed and residue was washed with methanol. The combined filtrate was concentrated under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420666B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-7de2674c31184f9e89e447183164d3c9 |
| Source note | uspto-grants-2013_04 |