HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dibutyltin dichloride → (4-Cyclopropylmethyl-3,4-dihydro-2H-quinoxalin-1-yl)-[4-(2,5-dichloro-phenoxy)-pyridin-3-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dibutyltin dichloride | HCID 12688 | — |
| Reactant | Phenylsilane | HCID 12752 | — |
| Reactant | Cyclopropanecarboxaldehyde | HCID 123114 | — |
| Reactant | [4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinoxalin-1-yl)-methanone | HCID 53311864 | — |
| Product | (4-Cyclopropylmethyl-3,4-dihydro-2H-quinoxalin-1-yl)-[4-(2,5-dichloro-phenoxy)-pyridin-3-yl]-methanone | HCID 53311867 | — |
Reaction Steps
The title compound was prepared in analogy to Example 5, from [4-(2,5-dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinoxalin-1-yl)-methanone (Example 3), cyclopropanecarboxaldehyde (commercially available; CAS RN 1489-69-6), dibutyltin dichloride and phenylsilane. Light brown solid (53%). MS (ESI): m/z=454.109 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420647B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-5c4973ffedb34d52b3ac1ddc411f577d |
| Source note | uspto-grants-2013_04 |