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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1966975Generated: October 25, 2026

[4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone → (4-Cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)(4-(2,5-dichloro-phenoxy)-pyridin-3-yl)-methanone

https://huagongshe.com/reaction/1966975

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanoneHCID 53311781—
Reactant1-Cyclopropyl-1,2,3,4-tetrahydroquinoxalineHCID 67320755—
Product(4-Cyclopropyl-3,4-dihydro-2H-quinoxalin-1-yl)(4-(2,5-dichloro-phenoxy)-pyridin-3-yl)-methanoneHCID 53311869—

Reaction Steps

The title compound was prepared in analogy to Example 1, from 4-(2,5-dichloro-phenoxy)-nicotinic acid (Example 1, intermediate) and 1-cyclopropyl-1,2,3,4-tetrahydro-quinoxaline. Light yellow foam (72%). MS (ESI): m/z=440.092 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420647B2
Source datasetuspto-grants-2013_04
ORD IDord-efff6322ee794cdca4f589d62f9515b7
Source noteuspto-grants-2013_04