HuagongsheHuagongshe Chemistry Print Report · For research reference only
1177351-07-3 → HCID 67320560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1177351-07-3 | HCID 43810527 | — |
| Reactant | [4-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone | HCID 53311781 | — |
| Solvent | Ethylacetate heptane | HCID 21899848 | — |
| Product | HCID 67320560 | HCID 67320560 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, from 4-(2,5-dichloro-phenoxy)-nicotinic acid (Example 1, intermediate), (2-amino-4-chlorphenyl)dimethylamine dihydrochloride (commercially available, CAS RN 183251-88-9), using 5 mole equivalents of base and using a gradient of n-heptane:ethyl acetate (100:0 to 50:50) for the chromatographic purification. White solid (72%). MS (ESI): m/z=436.038 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420647B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-c52ba9b83c664c63b14f1ec145ecd1c8 |
| Source note | uspto-grants-2013_04 |