HuagongsheHuagongshe Chemistry Print Report · For research reference only
{2,5-Dichloro-4-[3-(4-cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzoylamino}-acetic acid methyl ester → HCID 178523104, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {2,5-Dichloro-4-[3-(4-cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzoylamino}-acetic acid methyl ester | HCID 53312194 | — |
| Reactant | HCID 178510704 | HCID 178510704 | — |
| Product | HCID 178523104 | HCID 178523104 | 58% |
Reaction Steps
The title compound was prepared in analogy to Example 38, from 2,5-dichloro-4-[3-(4-cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzoic acid (Example 29, intermediate) and 5-(aminomethyl)-tetrazole (commercially available, CAS RN 31602-63-8) to provide 0.078 g (58%) of the title compound as a light yellow solid. MS (ESI): m/z=565.126 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420647B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-74c5f506d6a2492eb94604c1f2074563 |
| Source note | uspto-grants-2013_04 |