Benzene, 1-(chloromethyl)-3(or 4)-ethenyl- → HCID 131730513, compound

Participants

Reaction Steps

Monomer norbornenylethylstyrene (N) was first synthesized as shown in FIG. 1. Norbornenylmethyl bromide (mainly the endo isomer) was treated with magnesium in THF to form the corresponding Grignard reagent. In the presence of a catalytic amount of Li2CuCl4, this norbornenylmethyl magnesium bromide (1.15 equiv) was coupled with vinylbenzyl chloride (1 equiv) at −78° C. in THF to produce the p-norbornenylethylstyrene (N) in a conversion of 85%. The 13C and 1H NMR spectra of purified N (silica column/hexanes) indicated a product of high purity and all resonances were consistent with the structure.

Provenance & Evidence