2-Chlorobenzaldehyde → HCID 135871092, compound

Participants

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 2-Chlorobenzaldehyde (1 mmol) were combined in methanol (2 ml, dry). After 2 hours 2 ml of a solution of KOCN (KSCN) (2 mmol) and Pyridinehydrochloride (2 mmol) in MeOH is added was added. Finally 2-(2-Isocyano-ethyl)-thiophene (1 mmol) is added. The reaction was stirred at room temperature for 48 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence