HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzaldehyde → HCID 178517947, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzaldehyde | HCID 70741 | — |
| Reactant | 2,3-DIHYDRO-6-ISOCYANO-1,4-BENZODIOXINE | HCID 2734808 | — |
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 178418250 | HCID 178418250 | — |
| Reactant | HCID 178507353 | HCID 178507353 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178517947 | HCID 178517947 | — |
Reaction Steps
1H-Benzoimidazol-5-ylamine (1 mmol) and 4-Bromobenzaldehyde (1 mmol) were combined in methanol (2 ml, dry). After 2 hours 2 ml of a solution of KOCN (KSCN) (2 mmol) and Pyridinehydrochloride (2 mmol) in MeOH is added was added. Finally 6-Isocyano-2,3-dihydro-benzo[1,4]dioxine (μmol) is added. The reaction was stirred at room temperature for 48 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420684B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-8a072023145d4881b7ead805da1e07e6 |
| Source note | uspto-grants-2013_04 |