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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1967162Generated: October 31, 2026

4-[(4-Bromobenzene)sulfonyl]morpholine → HCID 44608154, compound

https://huagongshe.com/reaction/1967162

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(4-Bromobenzene)sulfonyl]morpholineHCID 253128—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
ProductHCID 44608154HCID 44608154—

Reaction Steps

5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[4-(morpholin-4-ylsulfonyl)phenyl]amino}thiophene-3-carboxamide was prepared according to the general procedure in Example 1 using 2-amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide (150 mg, 0.480 mmol) and 4-[(4-bromophenyl)sulfonyl]morpholine (147 mg, 0.480 mmol) as the starting materials.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08420695B2
Source datasetuspto-grants-2013_04
ORD IDord-bfa45d07708840969d6ba41efa4d42e0
Source noteuspto-grants-2013_04