Potassium Carbonate → HCID 12811505, compound

Participants

Reaction Conditions

Reaction Steps

1-bromo-4-(bromomethyl)benzene (300 mg, 1.200 mmol), 1H-1,2,3-triazole (84 μl, 1.440 mmol), and potassium carbonate (332 mg, 2.401 mmol) were taken up in dimethylformamide (1500 μl) and heated to 50° C. overnight. The reaction was quenched with water and extracted using ethyl acetate. The organic layers were combined, dried over magnesium sulfate, filtered, and concentrated under reduced pressure. Purification was performed via silica gel chromatography (50-100% ethyl acetate in hexanes) to yield the title compound.

Provenance & Evidence