HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetylene → HCID 25221838, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetylene | HCID 10821 | — |
| Reactant | HCID 44543018 | HCID 44543018 | — |
| Solvent | Dichloromethane heptane | HCID 21907733 | — |
| Product | HCID 25221838 | HCID 25221838 | — |
Reaction Steps
This product was prepared from toluene-4-sulfonic acid 1-methyl-5-trifluoromethyl-1H-pyrazol-3-yl ester and phenylacetylene following the general procedure for the Sonogashira cross-coupling reaction described above. Chromatography eluent: heptane/DCM 7:3; yield (19 mg, 15%); 1H NMR δ (CDCl3): 7.66-7.55 (m, 5H), 6.64 (s, 1H), 3.98 (s, 3H), LCMS m/z: 250.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420812B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-7b747c7abf184c1086c30844db73cb6d |
| Source note | uspto-grants-2013_04 |