HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 59556993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | 3,3,5-Trimethylpyrrolidine-2,4-dione | HCID 55299893 | — |
| Reactant | 4-Bromo-2-fluoro-3-methylbenzonitrile | HCID 59556913 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Product | HCID 59556993 | HCID 59556993 | — |
Reaction Steps
Using 3,3,5-trimethylpyrrolidine-2,4-dione (400 mg), 4-bromo-2-fluoro-3-methylbenzonitrile (667 mg), cesium carbonate (1.39 g), tris(dibenzylideneacetone)dipalladium(0) (130 mg) and 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (246 mg), and in the same manner as in Reference Example 18, the title compound was obtained as colorless crystals (yield: 137 mg, 18%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420694B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-1a6dd51f3c334e5abb2723b1728bda9e |
| Source note | uspto-grants-2013_04 |