HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196729Generated: October 30, 2026
Water → 4-Chloro-8-(2,4-dimethoxybenzyl)-5-(trifluoromethyl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one
https://huagongshe.com/reaction/196729
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2,4-Dimethoxybenzylamine | HCID 597250 | — |
| Reactant | Methyl 3-(4,6-dichloropyrimidin-5-yl)-4,4,4-trifluorobutanoate | HCID 86666569 | — |
| Reactant | Methyl 3-(4-chloro-6-(2,4-dimethoxybenzylamino)pyrimidin-5-yl)-4,4,4-trifluorobutanoate | HCID 86666570 | — |
| Product | 4-Chloro-8-(2,4-dimethoxybenzyl)-5-(trifluoromethyl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one | HCID 86666568 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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| ORD ID | ord-ea45ea6d58344be0a4e048de5fe60790 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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