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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 196729Generated: October 30, 2026

Water → 4-Chloro-8-(2,4-dimethoxybenzyl)-5-(trifluoromethyl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one

https://huagongshe.com/reaction/196729

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant2,4-DimethoxybenzylamineHCID 597250—
ReactantMethyl 3-(4,6-dichloropyrimidin-5-yl)-4,4,4-trifluorobutanoateHCID 86666569—
ReactantMethyl 3-(4-chloro-6-(2,4-dimethoxybenzylamino)pyrimidin-5-yl)-4,4,4-trifluorobutanoateHCID 86666570—
Product4-Chloro-8-(2,4-dimethoxybenzyl)-5-(trifluoromethyl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-oneHCID 86666568—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-ea45ea6d58344be0a4e048de5fe60790
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)