HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 59556948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | 4-Bromo-2-chlorobenzonitrile | HCID 7010420 | — |
| Reactant | HCID 59556931 | HCID 59556931 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Product | HCID 59556948 | HCID 59556948 | — |
Reaction Steps
Using 4-bromo-2-chlorobenzonitrile (556 mg), (4R,5S)-3,3-difluoro-4-hydroxy-5-methylpyrrolidin-2-one (448 mg), 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (219 mg), tris(dibenzylideneacetone)dipalladium(0) (113 mg) and cesium carbonate (1.18 g), and in the same manner as in Reference Example 3, the title compound was obtained as a white powder (yield: 34.2 mg, 5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420694B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-ab72fe1ae2a94a9a913881a6f86a1121 |
| Source note | uspto-grants-2013_04 |