HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 59557012, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | 2-Chloro-4-iodo-3-methylbenzonitrile | HCID 16731995 | — |
| Reactant | HCID 57577515 | HCID 57577515 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Product | HCID 59557012 | HCID 59557012 | — |
Reaction Steps
Using 2-chloro-4-iodo-3-methylbenzonitrile (478 mg), (4R,5S)-4-cyclopropyl-5-ethyl-4-hydroxypyrrolidin-2-one (350 mg), 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (153 mg), tris(dibenzylideneacetone)dipalladium(0) (79 mg) and cesium carbonate (786 mg), and in the same manner as in Example 62, the title compound was obtained as colorless crystals (yield: 78 mg, 14%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420694B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-03b83ec2f4804d24a83a20eeebf79819 |
| Source note | uspto-grants-2013_04 |