Boronic Acid → 2-(4'-Ethanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

HRID 196744Notes

Reaction equation

HRID 196744 reaction equation
[BH:1]([OH:2])[OH:3].[Br:15][c:16]1[cH:17][cH:18][c:19](-[c:22]2[o:23][c:24]([CH3:34])[c:25]([CH2:27][CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33]3)[n:26]2)[cH:20][cH:21]1.[CH2:4]([CH3:5])[S:6](=[O:7])(=[O:8])[c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1>>[CH2:4]([CH3:5])[S:6](=[O:7])(=[O:8])[c:9]1[cH:10][cH:11][c:12](-[c:16]2[cH:17][cH:18][c:19](-[c:22]3[o:23][c:24]([CH3:34])[c:25]([CH2:27][CH2:28][N:29]4[CH2:30][CH2:31][CH2:32][CH2:33]4)[n:26]3)[cH:20][cH:21]2)[cH:13][cH:14]1

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 69032(Ethylsulphonyl)benzeneHCID 116815462-(4-Bromo-phenyl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Product 1

HCID 115826382-(4'-Ethanesulfonyl-biphenyl-4-yl)-5-methyl-4-(2-pyrrolidin-1-yl-ethyl)-oxazole

Sources & evidence

ORD record
ord-b457f875048143a18b207ecd8daa5201
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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