4-(Trifluoromethyl)aniline → HCID 18268095, compound

HRID 1967491Notes

Reaction equation

HRID 1967491 reaction equation
[N:1]1([S:7]([C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13]([OH:15])=O)(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][CH:21]=1>>[N:1]1([S:7]([C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:27])([F:28])[F:29])=[CH:22][CH:21]=2)=[O:15])(=[O:8])=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 99644-(Trifluoromethyl)anilineHCID 7678893-(Piperidine-1-sulfonyl)benzoic acid

Product 1

HCID 18268095HCID 18268095, compound

Procedure

The entitled compound was produced according to the method of Example 71 but using 3-(piperidin-1-ylsulfonyl)benzoic acid (100 mg) and 4-aminobenzotrifluoride (59 mg) as the starting materials.

Workup

  1. customThe entitled compound was produced

Sources & evidence

ORD record
ord-af12c03928a345ba880e2c7f3559c2dd
Source dataset
uspto-grants-2013_04
Patent number
US08420823B2

Reaction notes

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