3-(Piperidine-1-sulfonyl)benzoic acid → HCID 178521743, compound
Reaction equation
[N:1]1([S:7]([C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13]([OH:15])=O)(=[O:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:19]1([C:22]2[NH:26][N:25]=[C:24]([NH2:27])[CH:23]=2)[CH2:21][CH2:20]1>>[CH:19]1([C:22]2[CH:23]=[C:24]([NH:27][C:13](=[O:15])[C:12]3[CH:16]=[CH:17][CH:18]=[C:10]([S:7]([N:1]4[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]4)(=[O:8])=[O:9])[CH:11]=3)[NH:25][N:26]=2)[CH2:21][CH2:20]1Participants
3
Procedure
The entitled compound was produced according to the method of Example 92 but using 3-(piperidin-1-ylsulfonyl)benzoic acid and 5-cyclopropyl-1H-pyrazole-3-amine as the starting materials.
Workup
- customThe entitled compound was produced
Sources & evidence
- ORD record
- ord-777a5c56ef02442f87d084ff46fe4bba
- Source dataset
- uspto-grants-2013_04
- Patent number
- US08420823B2
Reaction notes
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