3-(Pyrrolidine-1-sulfonyl)benzoic acid → N-(5-bromo-3-methoxypyridin-2-yl)-3-(pyrrolidin-1-ylsulfonyl)benzamide

HRID 1967524Notes

Reaction equation

HRID 1967524 reaction equation
[N:1]1([S:6]([C:9]2[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=2)[C:12]([OH:14])=O)(=[O:8])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:18][C:19]1[CH:20]=[C:21]([O:26][CH3:27])[C:22]([NH2:25])=[N:23][CH:24]=1>>[Br:18][C:19]1[CH:20]=[C:21]([O:26][CH3:27])[C:22]([NH:25][C:12](=[O:14])[C:11]2[CH:15]=[CH:16][CH:17]=[C:9]([S:6]([N:1]3[CH2:2][CH2:3][CH2:4][CH2:5]3)(=[O:7])=[O:8])[CH:10]=2)=[N:23][CH:24]=1

Participants

3

Reactant 2

HCID 7676903-(Pyrrolidine-1-sulfonyl)benzoic acidHCID 222714075-Bromo-3-methoxypyridin-2-amine

Product 1

HCID 66872379N-(5-bromo-3-methoxypyridin-2-yl)-3-(pyrrolidin-1-ylsulfonyl)benzamide

Procedure

The intended substance was produced according to the method of Example 92 but using 3-(pyrrolidin-1-ylsulfonyl)benzoic acid and 5-bromo-3-methoxypyridine-2-amine as the starting materials.

Workup

  1. customThe intended substance was produced

Sources & evidence

ORD record
ord-7d1c4949351f40d5ac713aceb81bc469
Source dataset
uspto-grants-2013_04
Patent number
US08420823B2

Reaction notes

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