Acetonitrile → [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-[3-(2-morpholin-4-yl-ethoxymethyl)-phenyl]-amine

HRID 196820Notes

Reaction equation

HRID 196820 reaction equation
[CH3:1][c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([CH2:21][OH:22])[cH:18][cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1.[CH3:32][C:33]#[N:34].[Cl:23][CH2:24][CH2:25][N:26]1[CH2:27][CH2:28][O:29][CH2:30][CH2:31]1>>[CH3:1][c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([CH2:21][O:22][CH2:24][CH2:25][N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[cH:18][cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 767274-(2-Chloroethyl)morpholineHCID 22744124{3-[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-ylamino]-phenyl}-methanol

Product 1

HCID 10002542[4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-[3-(2-morpholin-4-yl-ethoxymethyl)-phenyl]-amine

Sources & evidence

ORD record
ord-96be509c04b043b5b1e46ea58ff26f9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…