HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-tert-butyl 3-cyano-1-(cyclopentylamino)-1-oxopropan-2-ylcarbamate → HCID 67224236, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-tert-butyl 3-cyano-1-(cyclopentylamino)-1-oxopropan-2-ylcarbamate | HCID 67225088 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 67224236 | HCID 67224236 | 41% |
Reaction Steps
A mixture of (R)-tert-butyl 3-cyano-1-(cyclopentylamino)-1-oxopropan-2-ylcarbamate and 50% TFA/DCM (10 mL) was stirred for 1 h. Following reaction, the mixture was concentrated to afford the title compound as a clear oil (TFA salt, 0.265 g, 41%). The product was pure by TLC (visualized by ninhydrin stain).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08420816B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0c10f4419b914016bb369fba3931ce62 |
| Source note | uspto-grants-2013_04 |