N,N-dimethyl-2-(4-nitro-1H-pyrazol-1-yl)acetamide → 2-(4-amino-1H-pyrazol-1-yl)-N,N-dimethylacetamide

Participants

Reaction Steps

A solution of N,N-dimethyl-2-(4-nitro-1H-pyrazol-1-yl)acetamide (870 mg, 4.39 mmol) in methanol (22 ml) was evacuated/purged with nitrogen and treated with Pd on carbon (87 mg, 0.082 mmol). The resulting black suspension was evacuated/purged with a hydrogen balloon and stirred under the hydrogen overnight when the mixture was filtered through celite with methanol washes. The filtrate was concentrated to give the product.

Provenance & Evidence