HuagongsheHuagongshe Chemistry Print Report · For research reference only
[5-Fluoro-2-(methoxycarbonyl)phenyl]boronic acid → HCID 67144762, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [5-Fluoro-2-(methoxycarbonyl)phenyl]boronic acid | HCID 4374269 | — |
| Reactant | N-(Phenylthio)phthalimide | HCID 5127161 | — |
| Catalyst | HCID 178439318 | HCID 178439318 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67144762 | HCID 67144762 | — |
Reaction Steps
5-Fluoro-2-(methoxycarbonyl)phenylboronic acid (1.00 g), 2-(phenylthio)isoindoline-1,3-dione (0.86 g), and (2-hydroxy-3,5-diisopropylbenzoyloxy)copper (0.29 g) were stirred in dioxane (15 mL) at 50° C. for 24 hours. The reaction mixture was chromatographed on silica gel with 5% ethyl acetate/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426422B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-d265a9cf0aa04d37b619b703c02345d0 |
| Source note | uspto-grants-2013_04 |