Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chlorobenzylamine → HCID 178500503, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chlorobenzylamine | HCID 66036 | — |
| 반응물 | Pyruvic aldehyde dimethyl acetal | HCID 80650 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | HCID 178500503 | HCID 178500503 | 100% |
반응 단계
In a three-necked round bottomed flask equipped with a Dean Stark trap and reflux cooler, a solution of 4-chlorobenzylamine (97.3 g, 0.687 mol) and 1,1-dimethoxy-propan-2-one (89.5 g, 0.758 mol) in toluene (300 mL) was heated for 3 h at reflux. The reaction mixture was cooled down and the solvent removed in vacuo to yield the title compound as a pale yellow oil (166 g, 0.687 mol, 100%). MS (ES+): 242 (M(C12H1635ClNO2)+H)+. MS (ES+): 242 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08426440B2 |
| 출처 데이터셋 | uspto-grants-2013_04 |
| ORD ID | ord-2f5434dfe84e4697901b8409b5483956 |
| 출처 메모 | uspto-grants-2013_04 |