反应详情

(4-Methyl-2-nitrophenyl)methanol D139 (1.028 g, 6.15 mmol), pyridinium dichromate (3.47 g, 9.22 mmol)+molecular sieves (7 g, 6.15 mmol) in dry dichloromethane (DCM) (14 mL) was stirred under argon at R.T. overnight. The reaction mixture was filtered by silica/kieselguhr (1:1) and extracted with water and DCM. Organic layers were combined and evaporated to give a pale yellow solid which was used without further purification (0.665 g, 65.5%).

1. filtrationThe reaction mixture was filtered by silica/kieselguhr (1:1)
2. extractionextracted with water and DCM
3. customevaporated
4. customto give a pale yellow solid which
5. customwas used without further purification (0.665 g, 65.5%)