(1S,2R)-(-)-1-Amino-2-indanol → HCID 58237607, compound

HRID 1969030Notes

Reaction equation

HRID 1969030 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH:22]=O)[CH:7]=1)[CH3:2].[CH2:25]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[C@H:27]([NH2:34])[C@@H:26]1[OH:35]>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22][NH:34][C@H:27]2[C:28]3[C:33](=[CH:32][CH:31]=[CH:30][CH:29]=3)[CH2:25][C@H:26]2[OH:35])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 9866743(1S,2R)-(-)-1-Amino-2-indanolHCID 58237615[3-(4-Bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester

Product 1

HCID 58237607HCID 58237607, compound

Procedure

Prepared according to the procedure described in Example 3, Step 2, using the following starting materials: [3-(4-bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester and (1S,2R)-(−)-cis-1-amino-2-indanol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-db87920118344fcf84e16abe5e05f597
Source dataset
uspto-grants-2013_04
Patent number
US08426449B2

Reaction notes

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