1-Aminoindane, (S)- → HCID 58288528, compound

HRID 1969041Notes

Reaction equation

HRID 1969041 reaction equation
[CH3:1][O:2][C:3](=[O:24])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[CH:22]=O)[CH:6]=1.[NH2:25][C@@H:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27]1>>[CH3:1][O:2][C:3](=[O:24])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:20])([F:19])[F:21])=[CH:14][C:13]=2[CH2:22][NH:25][C@@H:26]2[C:34]3[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=3)[CH2:28][CH2:27]2)[CH:6]=1

Participants

3

Reactant 2

HCID 70000841-Aminoindane, (S)-HCID 58237636[3-(2-Formyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester

Product 1

HCID 58288528HCID 58288528, compound

Procedure

Prepared according to the procedure described in Example 3, Step 2, using the following starting materials: [3-(2-formyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester and (S)-(+)-1-aminoindan.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d345693cdfe4414a975260ef1ae6797f
Source dataset
uspto-grants-2013_04
Patent number
US08426449B2

Reaction notes

Loading…