Sodium borohydride → HCID 58288493, compound

Participants

Reaction Steps

To [3-(2-formyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid ethyl ester (0.411 g, 1.17 mmol) in MeOH (15 mL) was added sodium borohydride (0.045 g, 1.17 mmol), and the reaction was stirred for 15 minutes at room temperature. The mixture was concentrated, and the residue was partitioned between EtOAc and H2O. The aqueous layer was separated and extracted twice with EtOAc, and the combined organic layers were dried and concentrated to give the title compound.

Provenance & Evidence