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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969062Generated: October 30, 2026

2-Trifluoromethylbenzenesulphonyl chloride → [3-(2-{[Methyl-(2-trifluoromethyl-benzenesulfonyl)-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester

https://huagongshe.com/reaction/1969062

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Trifluoromethylbenzenesulphonyl chlorideHCID 136616—
Reactant[3-(2-Methylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl esterHCID 58288517—
Product[3-(2-{[Methyl-(2-trifluoromethyl-benzenesulfonyl)-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl esterHCID 58288542—

Reaction Steps

Prepared according to the procedure described in Example 22, Step 1, using the following starting materials: [3-(2-methylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester and 2-(trifluoromethyl)benzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426449B2
Source datasetuspto-grants-2013_04
ORD IDord-a67d2611d61c4aaea98d2ef29aaa1ae2
Source noteuspto-grants-2013_04