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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969065Generated: October 26, 2026

4-Toluenesulfonyl chloride → [3-(2-{[Ethyl-(toluene-4-sulfonyl)-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester

https://huagongshe.com/reaction/1969065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant[3-(2-Ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl esterHCID 58288538—
Product[3-(2-{[Ethyl-(toluene-4-sulfonyl)-amino]-methyl}-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl esterHCID 58288464—

Reaction Steps

Prepared according to the procedure described in Example 22, Step 1, using the following starting materials: [3-(2-ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester and p-toluenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426449B2
Source datasetuspto-grants-2013_04
ORD IDord-53cb4c3e86cc4cf3ab56989e155a0608
Source noteuspto-grants-2013_04