p-Bromobenzenesulfonyl chloride → HCID 58288537, compound

HRID 1969069Notes

Reaction equation

HRID 1969069 reaction equation
[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[CH2:22][NH:23][CH2:24][CH3:25])[CH:6]=1.[Br:27][C:28]1[CH:33]=[CH:32][C:31]([S:34](Cl)(=[O:36])=[O:35])=[CH:30][CH:29]=1>>[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:20])([F:19])[F:21])=[CH:14][C:13]=2[CH2:22][N:23]([S:34]([C:31]2[CH:32]=[CH:33][C:28]([Br:27])=[CH:29][CH:30]=2)(=[O:36])=[O:35])[CH2:24][CH3:25])[CH:6]=1

Participants

3

Reactant 2

HCID 7396p-Bromobenzenesulfonyl chlorideHCID 58288538[3-(2-Ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester

Product 1

HCID 58288537HCID 58288537, compound

Procedure

Prepared according to the procedure described in Example 22, Step 1, using the following starting materials: [3-(2-ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester and 4-bromobenzenesulfonyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-07505cfc674d40d5b13dc4e6dfe06409
Source dataset
uspto-grants-2013_04
Patent number
US08426449B2

Reaction notes

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