Methyl chloroformate → HCID 58288519, compound

HRID 1969081Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:33])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:14]=2[CH2:22][NH:23][C@@H:24]([CH3:32])[CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:7]=1)[CH3:2].Cl[C:35]([O:37][CH3:38])=[O:36]>>[CH2:1]([O:3][C:4](=[O:33])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:14]=2[CH2:22][N:23]([C:35]([O:37][CH3:38])=[O:36])[C@@H:24]([CH3:32])[CH2:25][C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:7]=1)[CH3:2]

Participants

Reactant 2

HCID 6586Methyl chloroformate

HCID 58288492HCID 58288492, compound

Product 1

HCID 58288519HCID 58288519, compound

Procedure

Prepared according to the procedure described in Example 3, Step 3, using the following starting materials: (3-{2-[((S)-1-methyl-2-phenyl-ethylamino)-methyl]-4-nitro-phenoxy}-phenyl)-acetic acid ethyl ester and methyl chloroformate.

Workup

customPrepared

Sources & evidence

ORD record: ord-1bd6c318ec6b4b25993c0bd4c8de564b
Source dataset: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08426449B2

Reaction notes

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