4-Chlorobenzoyl chloride → HCID 58288512, compound

HRID 1969095Notes

Reaction equation

HRID 1969095 reaction equation
[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=2[CH2:22][N:23]([C:26](=[O:28])[CH3:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2].[Cl:30][C:31]1[CH:39]=[CH:38][C:34]([C:35](Cl)=[O:36])=[CH:33][CH:32]=1>>[CH2:1]([O:3][C:4](=[O:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:35](=[O:36])[C:34]3[CH:38]=[CH:39][C:31]([Cl:30])=[CH:32][CH:33]=3)=[CH:17][C:16]=2[CH2:22][N:23]([C:26](=[O:28])[CH3:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 58288483HCID 58288483, compound

Product 1

HCID 58288512HCID 58288512, compound

Procedure

Prepared according to the procedure described in Example 42, Step 5, using the following starting materials: (3-{2-[(acetyl-ethyl-amino)-methyl]-4-amino-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester and 4-chlorobenzoyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-42a9123566c34e608be9c81bb60ddc42
Source dataset
uspto-grants-2013_04
Patent number
US08426449B2

Reaction notes

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