Pivaloyl chloride → HCID 58288518, compound

HRID 1969098Notes

Reaction equation

HRID 1969098 reaction equation
[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=2[CH2:22][N:23]([C:26]([CH:28]2[CH2:30][CH2:29]2)=[O:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2].[CH3:32][C:33]([CH3:38])([CH3:37])[C:34](Cl)=[O:35]>>[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:34](=[O:35])[C:33]([CH3:38])([CH3:37])[CH3:32])=[CH:17][C:16]=2[CH2:22][N:23]([C:26]([CH:28]2[CH2:29][CH2:30]2)=[O:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 62493Pivaloyl chlorideHCID 58288501HCID 58288501, compound

Product 1

HCID 58288518HCID 58288518, compound

Procedure

Prepared according to the procedure described in Example 42, Step 5, using the following starting materials: (3-{4-amino-2-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester and trimethylacetyl chloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2bae3d0e547f4f2aaf909bc85ee9e0f9
Source dataset
uspto-grants-2013_04
Patent number
US08426449B2

Reaction notes

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