HRID1969099

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8501

4-Chlorobenzoyl chloride

C7H4Cl2O

HCID58288501

未命名化合物

PRODUCTS

产物

HCID58288521

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 42, Step 5, using the following starting materials: (3-{4-amino-2-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester and 4-chlorobenzoyl chloride.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-ac2a7fdcd7054915b1ab56d4fc33d778
来源数据集: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08426449B2
来源说明: uspto-grants-2013_04

反应SMILES

[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH2:21])=[CH:17][C:16]=2[CH2:22][N:23]([C:26]([CH:28]2[CH2:30][CH2:29]2)=[O:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2].[Cl:32][C:33]1[CH:41]=[CH:40][C:36]([C:37](Cl)=[O:38])=[CH:35][CH:34]=1>>[CH2:1]([O:3][C:4](=[O:31])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([NH:21][C:37](=[O:38])[C:36]3[CH:40]=[CH:41][C:33]([Cl:32])=[CH:34][CH:35]=3)=[CH:17][C:16]=2[CH2:22][N:23]([C:26]([CH:28]2[CH2:29][CH2:30]2)=[O:27])[CH2:24][CH3:25])[CH:7]=1)[CH3:2]