HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(6-Chloropyridine-3-carbonyl)morpholine → HCID 44198081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(6-Chloropyridine-3-carbonyl)morpholine | HCID 857499 | — |
| Reactant | 2-(Dicyclohexylphosphino)biphenyl | HCID 2734216 | — |
| Reactant | Sodium t-butoxide | HCID 23676156 | — |
| Reactant | HCID 42643655 | HCID 42643655 | — |
| Product | HCID 44198081 | HCID 44198081 | — |
Reaction Conditions
| Temperature | 200 °C |
|---|
Reaction Steps
A mixture of N-[3-(8-Amino-imidazo[1,2-a]pyridin-6-yl)-2-methyl-phenyl]-4-tert-butyl-benzamide (0.69 g, 1.73 mmol), (6-Chloro-pyridin-3-yl)-morpholin-4-yl-methanone (1.17 g, 5.19 mmol), sodium t-butoxide (0.23 g, 2.42 mmol), Pd(II)acetate (19 mg, 0.08 mmol) and 2-(dicyclohexyl-phosphino)biphenyl was stirred at 200° C. in a microwave for 100 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426441B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-787db149e50c45aa83fbd2550ed16cc8 |
| Source note | uspto-grants-2013_04 |