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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969133Generated: October 25, 2026

N-bromobutanimide → Methyl 2-(3-bromo-5-cyano-4-hydroxyphenyl)isonicotinate

https://huagongshe.com/reaction/1969133

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
ReactantMethyl 2-(3-cyano-4-hydroxyphenyl)isonicotinateHCID 136368377—
SolventAcetonitrileHCID 6342—
ProductMethyl 2-(3-bromo-5-cyano-4-hydroxyphenyl)isonicotinateHCID 136368379—

Reaction Steps

Methyl 2-(3-cyano-4-hydroxyphenyl)isonicotinate and N-bromosuccinimide were stirred at room temperature in acetonitrile to obtain methyl 2-(3-bromo-5-cyano-4-hydroxyphenyl)isonicotinate. FN: 333.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426453B2
Source datasetuspto-grants-2013_04
ORD IDord-57d10c2db03c40d1a530544610651dd3
Source noteuspto-grants-2013_04