HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(4-azido-3-cyanophenyl)isonicotinate → Methyl 2-(4-amino-3-cyanophenyl)isonicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(4-azido-3-cyanophenyl)isonicotinate | HCID 86626138 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-(4-amino-3-cyanophenyl)isonicotinate | HCID 66995476 | — |
Reaction Steps
Palladium-carbon was added to a methanol solution of methyl 2-(4-azido-3-cyanophenyl)isonicotinate, and the mixture was stirred in the presence of hydrogen gas at room temperature for 5 hours to obtain methyl 2-(4-amino-3-cyanophenyl)isonicotinate. AP: 254.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426453B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-8e8a931f714e4f8db4a2130cb9bd3ba1 |
| Source note | uspto-grants-2013_04 |