Succinic anhydride → HCID 24873251, compound

HRID 1969165Notes

Reaction equation

HRID 1969165 reaction equation
[OH:1][C:2]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:3]=1[C:4]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:5].[C:18]1(=[O:24])[O:23][C:21](=[O:22])[CH2:20][CH2:19]1>C(Cl)Cl>[C:21]([CH2:20][CH2:19][C:18]([O:17][C:15]1[CH:14]=[CH:13][C:3]([C:4]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:5])=[C:2]([OH:1])[CH:16]=1)=[O:24])([OH:23])=[O:22]

Participants

4

Reactant 2

HCID 7922Succinic anhydrideHCID 53440893Hexyl 2,4-dihydroxybenzoate

Product 1

HCID 24873251HCID 24873251, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

n-Hexyl 2,4-dihydroxybenzoate (2 g) is dissolved in 25 mL of methylene chloride. To the solution, 0.85 g of succinic anhydride and 1.05 g of 4-N,N-dimethylpyridene are added. The reaction mixture is allowed to stir at ambient conditions overnight. The reaction mixture is extracted with 1 N HCl, water and saturated sodium chloride solution. The organic layer is dried over anhydrous sodium sulfate. Solvent is removed under reduced pressure to yield the product as an off-white powder.

Workup

  1. extractionThe reaction mixture is extracted with 1 N HCl, water and saturated sodium chloride solution
  2. dry with materialThe organic layer is dried over anhydrous sodium sulfate
  3. customSolvent is removed under reduced pressure

Sources & evidence

ORD record
ord-91eb5df54b7840f585710b1e773964ed
Source dataset
uspto-grants-2013_04
Patent number
US08426466B2

Reaction notes

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