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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1969290Generated: October 30, 2026

4-(2-Propyn-1-yl)morpholine → {4-[3-Isobutoxy-5-(3-morpholin-4-yl-prop-1-ynyl)-phenylsulfanyl]-2,5-dimethyl-phenoxy}-acetic Acid Ethyl Ester

https://huagongshe.com/reaction/1969290

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Propyn-1-yl)morpholineHCID 412941—
Reactant[4-(3-Bromo-5-isobutoxy-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic Acid Ethyl EsterHCID 57791907—
Product{4-[3-Isobutoxy-5-(3-morpholin-4-yl-prop-1-ynyl)-phenylsulfanyl]-2,5-dimethyl-phenoxy}-acetic Acid Ethyl EsterHCID 67170803—

Reaction Steps

The title product was prepared from [4-(3-Bromo-5-isobutoxy-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl ester (400 mg; 0.86 mmol) and 4-prop-2-ynyl-morpholine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426473B2
Source datasetuspto-grants-2013_04
ORD IDord-f971269edac2472ca4e20f64749eea0b
Source noteuspto-grants-2013_04