HCID 23394355, compound → HCID 68441695, compound

HRID 1969325Notes

Reaction equation

HRID 1969325 reaction equation
[F:1]/[C:2](/[CH2:13]Br)=[CH:3]/[CH2:4][NH:5]C(=O)OC(C)(C)C.[OH:15][C:16]1[C:30]([Cl:31])=[CH:29][C:19]([C:20]([NH:22][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[O:21])=[CH:18][C:17]=1[Cl:32]>>[ClH:31].[NH2:5][CH2:4]/[CH:3]=[C:2](/[F:1])\[CH2:13][O:15][C:16]1[C:17]([Cl:32])=[CH:18][C:19]([C:20]([NH:22][CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)=[O:21])=[CH:29][C:30]=1[Cl:31]

Participants

3

Reactant 2

HCID 23394355HCID 23394355, compoundHCID 68440952HCID 68440952, compound

Product 1

HCID 68441695HCID 68441695, compound

Procedure

(E)-4-(4-Amino-2-fluorobut-2-enyloxy)-3,5-dichloro-N-cyclohexylbenzamide hydrochloride was synthesized from (E)-tert-butyl 3-fluoro-4-bromobut-2-enylcarbamate and 4-hydroxy-3,5-dichloro-N-cyclohexylbenzamide.

Sources & evidence

ORD record
ord-c81278a6d9a043a4b0a4469ccc4745c1
Source dataset
uspto-grants-2013_04
Patent number
US08426587B2

Reaction notes

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